Neurocognitive development of children 4 years after critical illness and treatment with tight glucose control: a randomized controlled trial.

Abstract

CONTEXT A large randomized controlled trial revealed that tight glucose control (TGC) to age-adjusted normoglycemia (50-80 mg/dL at age <1 year and 70-100 mg/dL at age 1-16 years) reduced intensive care morbidity and mortality compared with usual care (UC), but increased hypoglycemia (≤40 mg/dL) (25% vs 1%). OBJECTIVE As both hyperglycemia and… (More)

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