Neurochemical studies on the mechanism of action of pyritinol.

  title={Neurochemical studies on the mechanism of action of pyritinol.},
  author={H. Greiner and A. Haase and C. Seyfried},
  volume={21 Suppl 1},
  • H. Greiner, A. Haase, C. Seyfried
  • Published 1988
  • Biology, Medicine
  • Pharmacopsychiatry
  • In investigations carried out in young and old rats with pyritinol (pyrithioxin, Encephabol), a substance that is frequently applied in cognitive function disturbances, besides effects on general cerebral functions, possible interactions with cholinergic transmission were determined. The following results were obtained: 1. The adenosine triphosphate (ATP) content of the blood was determined as a possible biochemical parameter of erythrocyte flexibility. After acute oral administration of 30… CONTINUE READING
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