Neurochemical profiles of some novel psychoactive substances.

@article{Iversen2013NeurochemicalPO,
  title={Neurochemical profiles of some novel psychoactive substances.},
  author={LeslieL. Iversen and Simon Gibbons and Ric Treble and Vincent Setola and Xi-Ping Huang and Bryan L. Roth},
  journal={European journal of pharmacology},
  year={2013},
  volume={700 1-3},
  pages={
          147-51
        }
}

• LeslieL. Iversen, Simon Gibbons, +3 authors Bryan L. Roth
• Published in European journal of pharmacology 2013
• DOI:10.1016/j.ejphar.2012.12.006

Fourteen substances from the class of drugs sometimes known as "legal highs" were screened against a battery of human receptors in binding assays, and their potencies as inhibitors of monoamine uptake determined in functional in vitro assays. Thirteen of the test substances acted as inhibitors of monoamine uptake at submicromolar concentrations, including 9 potent inhibitors of the dopamine transporter (DAT), 12 potent inhibitors of the norepinephrine transporter (NET) and 4 potent inhibitors… CONTINUE READING

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