Neurochemical basis of cannabis addiction

  title={Neurochemical basis of cannabis addiction},
  author={R. Maldonado and F. Berrendero and A. Ozaita and P. Robledo},
  • R. Maldonado, F. Berrendero, +1 author P. Robledo
  • Published 2011
  • Psychology, Medicine
  • Neuroscience
  • Cannabis derivatives have become the most widely used illicit substances in developed countries, and constitute a major health concern. The psychoactive compounds contained in cannabis induce their pharmacological effects by the activation of at least two different receptors, CB1 and CB2 cannabinoid receptors. Multiple studies have demonstrated the specific involvement of CB1 cannabinoid receptors in the addictive properties of cannabinoids. Several neurotransmitter systems involved in the… CONTINUE READING
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