Neuroblastoma: current drug therapy recommendations as part of the total treatment approach.

@article{Berthold2000NeuroblastomaCD,
  title={Neuroblastoma: current drug therapy recommendations as part of the total treatment approach.},
  author={Frank Berthold and Barabara Hero},
  journal={Drugs},
  year={2000},
  volume={59 6},
  pages={
          1261-77
        }
}
Neuroblastoma represents one of the most challenging malignancies for treatment decisions because of its unusual biological behaviour. The features include spontaneous regression (regressive type), maturation to ganglioneuroma (maturative type) and largely treatment-resistant progression (progressive type). Current knowledge allows only partial prediction of type. For practical reasons, patients may be categorised as an 'observation', a 'standard risk' or a 'high risk' treatment arm. During the… CONTINUE READING

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