Neuroblastoma: biological insights into a clinical enigma

@article{Brodeur2003NeuroblastomaBI,
  title={Neuroblastoma: biological insights into a clinical enigma},
  author={G. Brodeur},
  journal={Nature Reviews Cancer},
  year={2003},
  volume={3},
  pages={203-216}
}
  • G. Brodeur
  • Published 2003
  • Medicine
  • Nature Reviews Cancer
  • Neuroblastoma is a tumour derived from primitive cells of the sympathetic nervous system and is the most common solid tumour in childhood. Interestingly, most infants experience complete regression of their disease with minimal therapy, even with metastatic disease. However, older patients frequently have metastatic disease that grows relentlessly, despite even the most intensive multimodality therapy. Recent advances in understanding the biology and genetics of neuroblastomas have allowed… CONTINUE READING

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