Neurobiology of schizophrenia.

  title={Neurobiology of schizophrenia.},
  author={Godfrey D. Pearlson},
  journal={Annals of neurology},
  volume={48 4},
Schizophrenia is a common chronic and disabling brain disease of unknown etiology, pathogenesis, and mechanism. Whether schizophrenia represents a single disorder of markedly variable expression or a family of clinically related disorders is unclear. Genetic factors, most likely multiple genes of modest effect, play a major role in its etiology, but an environmental "second hit" may be necessary for clinical expression. The inherited biological susceptibility to schizophrenia is probably… CONTINUE READING
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