Neurobiology of relapse to heroin and cocaine seeking: an update and clinical implications.

Abstract

The central problem in the treatment of cocaine and heroin addiction is high rates of relapse to drug use after periods of forced or self-imposed abstinence. Relapse can be modeled in laboratory animals a reinstatement procedure in which responding for drug is extinguished and then reinstated by acute exposure to the drug, drug cues, or stress. In this… (More)

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Cite this paper

@article{Bossert2005NeurobiologyOR, title={Neurobiology of relapse to heroin and cocaine seeking: an update and clinical implications.}, author={Jennifer M Bossert and Udi E. Ghitza and Lin Lu and David H. Epstein and Yavin Shaham}, journal={European journal of pharmacology}, year={2005}, volume={526 1-3}, pages={36-50} }