Neurobiology of nitric oxide.

  title={Neurobiology of nitric oxide.},
  author={H. Y. Yun and Valina L Dawson and Ted M Dawson},
  journal={Critical reviews in neurobiology},
  volume={10 3-4},
Nitric oxide is a ubiquitous and unique biological messenger molecule. It mediates blood vessel relaxation by endothelium, immune function of macrophages, and neurotransmission of central and peripheral nervous systems. Endothelial and neuronal nitric oxide synthases are constitutively expressed and activated by calcium entry into cells, whereas the macrophage nitric oxide synthase is inducible with new RNA and protein synthesis upon immune stimulation. Nitric oxide may play a role in the… CONTINUE READING


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