• Corpus ID: 44591235

Neurobiology of behaviour. Editorial overview.

  title={Neurobiology of behaviour. Editorial overview.},
  author={John H. Byrne and Wendy A. Suzuki},
  journal={Current opinion in neurobiology},
  volume={16 6},
John H Byrne is currently the Professor and Chairman of the Department of Neurobiology and Anatomy and Director of the Neuroscience Research Center at the University of Texas Medical School at Houston. He is also the Director of the WM Keck Center for the Neurobiology of Learning and Memory at the UT Health Science Center. His research uses a combination of experimental and computational approaches to understand the cellular and molecular mechanisms of learning and memory. 


Reactivation of hippocampal ensemble memories during sleep.
Recordings from large ensembles of hippocampal "place cells" in three rats showed that cells that fired together when the animal occupied particular locations in the environment exhibited an increased tendency to fire together during subsequent sleep, in comparison to sleep episodes preceding the behavioral tasks.
Influences of hippocampal place cell firing in the awake state on the activity of these cells during subsequent sleep episodes
  • C. Pavlides, J. Winson
  • Biology
    The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1989
The findings suggest that neuronal activity of hippocampal place cells in the awake states may influence the firing characteristics of these cells in subsequent sleep episodes, and increased firing rates along with the greater number of multiple spike bursts and the shorter interspike intervals within the burst, following exposure to a cell's place field, may represent possible information processing during sleep.
Replay and Time Compression of Recurring Spike Sequences in the Hippocampus
It is hypothesized that the endogenously expressed spike sequences during sleep reflect reactivation of the circuitry modified by previous experience and serve to consolidate information in neuronal networks.