Neurobiology of animal models of attention-deficit hyperactivity disorder.

  title={Neurobiology of animal models of attention-deficit hyperactivity disorder.},
  author={Vivienne Ann Russell},
  journal={Journal of neuroscience methods},
  volume={161 2},
Attention-deficit hyperactivity disorder (ADHD) is a heterogeneous, highly heritable, disorder resulting from complex gene-gene and gene-environment interactions. The defining symptoms of hyperactivity, impulsivity and impaired sustained attention are not unique to ADHD. It is therefore not surprising that animals with distinctly different neural defects model the behavioural characteristics of the disorder. Consistent with ADHD being a developmental disorder, animal models are either genetic… CONTINUE READING