Neurobiology of HIV.

@article{Hult2008NeurobiologyOH,
  title={Neurobiology of HIV.},
  author={Britta J. Hult and Gursharan Chana and Eliezer Masliah and Ian Everall},
  journal={International review of psychiatry},
  year={2008},
  volume={20 1},
  pages={3-13}
}
The importance of HIV cognitive impairment, including HIV associated dementia (HAD) and minor cognitive/motor disorder, has continued in the era of highly active antiretroviral therapy (HAART). Despite the relative efficacy of HAART in controlling HIV disease, there is no treatment which specifically targets the cause of HAD nor promotes neuronal protection from the effects of the virus. Much work has been done to elucidate the complex signalling pathways, effects of virus and viral proteins… CONTINUE READING

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It is widely accepted that the majority of viral replication in the brain occurs in monocyte derived macrophages ( MDM ) and microglia , and immune activation of these cells , along with astrocytic cells , may be the most important cause of neurotoxicity in the central nervous system ( CNS ) .
It is widely accepted that the majority of viral replication in the brain occurs in monocyte derived macrophages ( MDM ) and microglia , and immune activation of these cells , along with astrocytic cells , may be the most important cause of neurotoxicity in the central nervous system ( CNS ) .
It is widely accepted that the majority of viral replication in the brain occurs in monocyte derived macrophages ( MDM ) and microglia , and immune activation of these cells , along with astrocytic cells , may be the most important cause of neurotoxicity in the central nervous system ( CNS ) .
It is widely accepted that the majority of viral replication in the brain occurs in monocyte derived macrophages ( MDM ) and microglia , and immune activation of these cells , along with astrocytic cells , may be the most important cause of neurotoxicity in the central nervous system ( CNS ) .
The importance of HIV cognitive impairment , including HIV associated dementia ( HAD ) and minor cognitive / motor disorder , has continued in the era of highly active antiretroviral therapy ( HAART ) .
The importance of HIV cognitive impairment , including HIV associated dementia ( HAD ) and minor cognitive / motor disorder , has continued in the era of highly active antiretroviral therapy ( HAART ) .
The importance of HIV cognitive impairment , including HIV associated dementia ( HAD ) and minor cognitive / motor disorder , has continued in the era of highly active antiretroviral therapy ( HAART ) .
The importance of HIV cognitive impairment , including HIV associated dementia ( HAD ) and minor cognitive / motor disorder , has continued in the era of highly active antiretroviral therapy ( HAART ) .
Further exploration of the molecular mechanisms leading to HIV neurotoxicity and neurodegeneration may reveal targets for prophylactic neuroprotective or other CNS - specific drugs .
It is widely accepted that the majority of viral replication in the brain occurs in monocyte derived macrophages ( MDM ) and microglia , and immune activation of these cells , along with astrocytic cells , may be the most important cause of neurotoxicity in the central nervous system ( CNS ) .
Further exploration of the molecular mechanisms leading to HIV neurotoxicity and neurodegeneration may reveal targets for prophylactic neuroprotective or other CNS - specific drugs .
The importance of HIV cognitive impairment , including HIV associated dementia ( HAD ) and minor cognitive / motor disorder , has continued in the era of highly active antiretroviral therapy ( HAART ) .
The importance of HIV cognitive impairment , including HIV associated dementia ( HAD ) and minor cognitive / motor disorder , has continued in the era of highly active antiretroviral therapy ( HAART ) .
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