Neurobiology of Addiction.

@article{Horseman2019NeurobiologyOA,
  title={Neurobiology of Addiction.},
  author={Casia Horseman and Avery M Meyer},
  journal={Clinical obstetrics and gynecology},
  year={2019},
  volume={62 1},
  pages={
          118-127
        }
}
Drugs of abuse can cause changes in the brain leading to addiction. Current scientific focus has been on how these drugs interact with the brain and the changes they cause, how those changes affect human behavior and how they may last beyond termination of drug use. Compulsiveness in seeking the drug, impulsiveness in consuming the drug, and negative affect when the drug is withheld are characteristic of addiction. Each of these characteristics has a root in neurobiology and understanding their… 
View on PubMed
ovid.com
3 Citations

3 Citations

Citation Type

Citation Type

Relative addictive potential of opioid analgesic agents.
TLDR
Providers should consider the risk of addiction with the opioids they prescribe and give those with a lower addictive potential a chance of survival.
The Periaqueductal Gray and Its Extended Participation in Drug Addiction Phenomena.
TLDR
The involvement of the PAG in drug addiction is discussed mainly via its role as an integrator of responses to the physical discomfort associated with drug withdrawal.
Oleanolic Acid Attenuates Morphine Withdrawal Symptoms in Rodents: Association with Regulation of Dopamine Function
TLDR
OA can improve the withdrawal symptoms of rats and mice by regulating the DA system and suggest that OA may be useful in treatment of morphine addiction.

References

SHOWING 1-3 OF 3 REFERENCES
Neurobiology of addiction. An integrative review.
  • A. Goodman
  • Psychology, Biology
    Biochemical pharmacology
  • 2008
Neurocircuitry of Addiction
TLDR
The delineation of the neurocircuitry of the evolving stages of the addiction syndrome forms a heuristic basis for the search for the molecular, genetic, and neuropharmacological neuroadaptations that are key to vulnerability for developing and maintaining addiction.
Drug Addiction, Dysregulation of Reward, and Allostasis