Neurobiology and cellular pathogenesis of glycolipid storage diseases.

@article{Walkley2003NeurobiologyAC,
  title={Neurobiology and cellular pathogenesis of glycolipid storage diseases.},
  author={Steven U Walkley},
  journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  year={2003},
  volume={358 1433},
  pages={893-904}
}
  • Steven U Walkley
  • Published 2003 in
    Philosophical transactions of the Royal Society…
Disorders of lysosomal metabolism often involve the accumulation of specific types of glycolipid, particularly gangliosides, because of either degradative failure or other currently unknown mechanisms. Although the precise role of gangliosides in cells remains enigmatic, the presence of specific abnormalities secondary to ganglioside accumulation in lysosomal diseases has suggested important biological functions. Chief among these is the growth of new dendrites on particular classes of mature… CONTINUE READING