Neurobiological studies of sensory gating in schizophrenia.

@article{Freedman1987NeurobiologicalSO,
  title={Neurobiological studies of sensory gating in schizophrenia.},
  author={Robert Freedman and Lawrence E. Adler and Greg A. Gerhardt and Merilyne Waldo and Neil J. Baker and Gregory M. Rose and Carla Drebing and Hisashi Nagamoto and Paula C. Bickford-Wimer and Ronald D. Franks},
  journal={Schizophrenia bulletin},
  year={1987},
  volume={13 4},
  pages={
          669-78
        }
}
The sensory disturbance in schizophrenia is often described as an inability to filter out extraneous noise from meaningful sensory inputs. The neurobiological basis of this inability to filter has been examined using auditory evoked potentials, which are computerized averages of the brain's electrical response to sound. The sounds are presented in pairs to test the ability of the brain to inhibit, or gate, its response to a repeated stimulus. Schizophrenic patients lack the ability to gate the… CONTINUE READING

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