Neurobiological studies of fatigue.

  title={Neurobiological studies of fatigue.},
  author={Mary E. Harrington},
  journal={Progress in neurobiology},
  volume={99 2},
Fatigue is a symptom associated with many disorders, is especially common in women and in older adults, and can have a huge negative influence on quality of life. Although most past research on fatigue uses human subjects instead of animal models, the use of appropriate animal models has recently begun to advance our understanding of the neurobiology of fatigue. In this review, results from animal models using immunological, developmental, or physical approaches to study fatigue are described… CONTINUE READING