Neurobiological mechanisms controlling aggression: preclinical developments for pharmacotherapeutic interventions.

@article{Miczek1994NeurobiologicalMC,
  title={Neurobiological mechanisms controlling aggression: preclinical developments for pharmacotherapeutic interventions.},
  author={K A Miczek and Elise M Weerts and M L Haney and Jennifer W. Tidey},
  journal={Neuroscience and biobehavioral reviews},
  year={1994},
  volume={18 1},
  pages={97-110}
}
Current pharmacotherapeutic approaches to the management of violent and aggressive behavior rely mostly on agents that act as receptor agonists or antagonists at subtypes of brain dopaminergic, GABAergic, and serotonergic receptors. Ethological experimental studies in animals have shown that drugs may modulate aggression by inhibiting motor activity, by distorting aggression-provoking or -inhibiting signals, by fragmenting behavioral sequences or temporal patterning, or by increasing the rate… CONTINUE READING