Neurobehavioural mechanisms of reward and motivation

@article{Robbins1996NeurobehaviouralMO,
  title={Neurobehavioural mechanisms of reward and motivation},
  author={Trevor William Robbins and Barry J. Everitt},
  journal={Current Opinion in Neurobiology},
  year={1996},
  volume={6},
  pages={228-236}
}

Figures from this paper

The Reward Signal of Midbrain Dopamine Neurons.

  • W. Schultz
  • Biology, Psychology
    News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
  • 1999
Dopamine projections from the midbrain to striatum and frontal cortex play a major role in behavioral reactions controlled by rewards and signal a crucial learning term for approach behavior.

Multiple reward signals in the brain

  • W. Schultz
  • Biology, Psychology
    Nature Reviews Neuroscience
  • 2000
Recent neurophysiological studies in primates that have revealed that neurons in a limited number of brain structures carry specific signals about past and future rewards provide the first step towards an understanding of how rewards influence behaviour before they are received.

Dopamine neurons and their role in reward mechanisms

  • W. Schultz
  • Biology, Psychology
    Current Opinion in Neurobiology
  • 1997

Striatal Dopamine and the Interface between Motivation and Cognition

It is hypothesized that an arrangement of spiraling connections between the midbrain and thestriatum that subserves a mechanism by which dopamine can direct information flow from ventromedial to more dorsal regions in the striatum provide the basis for functionally specific effects of appetitive motivation on cognition.

Cognitive Decision Processes and Functional Characteristics of the Basal Ganglia Reward System

This chapter proposes that both midbrain dopaminergic and striatal cholinergic intemeurons (TANs) continuously emit a complex tri-phasic neural message (neural signature of reward) which is modulated by the fitness of the environment to the animal predictions.

fMRI Investigations of the Mesolimbic Dopaminergic Reward System in Schizophrenia

Using the monetary incentive delay (MID) task, activation of the ventral striatum to incentive stimuli can be studied in an excellent way and shows that fMRI tasks are well suitable to investigate important aspects of schizophrenia pathophysiology.

Expectation of reward modulates cognitive signals in the basal ganglia

The results indicate that the caudate contributes to the determination of oculomotor outputs by connecting motivational values (for example, expectation of reward) to visual information.

Associative Processes in Addiction and Reward The Role of Amygdala‐Ventral Striatal Subsystems

Understanding of the special role of the ventral striatum is enriched in coordinating the contribution of different functional subsystems to confer flexibility, as well as coherence and vigor, to goal‐directed behavior, through different forms of associative learning.

Considerations upon the anatomical model of reward-based learning in the basal ganglia.

Two additional pathways are presented that may be related with the neurophysiological finding that the connections of the paralimbic cortices with the ventral system of the basal ganglia and then with the thalamus and the hypothalamus, and the circuit ventral striatum-substantia nigra pars reticulata-thalamus-striatum could be also involved in the reward-based learning.

Reward‐Related Responses in the Human Striatum

  • M. Delgado
  • Psychology, Biology
    Annals of the New York Academy of Sciences
  • 2007
The goal of this article is to probe the human reward circuit, specifically the striatum and its subdivisions, with an emphasis on how the affective properties of outcomes or feedback influence the underlying neural activity and subsequent decision making.
...

References

SHOWING 1-10 OF 56 REFERENCES

Neurobiology of opiate abuse.

Limbic-striatal interactions in reward-related processes

Dopamine, addiction and reward

Involvement of Mesolimbic Dopamine Neurons in Sexual Behaviors: Implications for the Neurobiology of Motivation

Evidence implicating the mesoaccumbens dopamine projection in sexual behaviors is reviewed and some of the issues that have contributed to the uncertainty over the exact role of this system are discussed.

Behavioral associations of neuronal activity in the ventral tegmental area of the rat

A clear demonstration that VTA neuronal activity is modulated during motivated behavior is provided, and similar information about events within the ongoing response/reinforcement cycle appears to be distributed through many neurons within the VTA, and may be mirrored in target structures such as PFC.

Neurobiology of motivation: double dissociation of two motivational mechanisms mediating opiate reward in drug-naive versus drug-dependent animals.

Second dopaminergic opiate reward mechanism mediates morphine's alleviation of the withdrawal distress associated with abstinence in opiate-dependent animals, and neuroleptic-induced blockade of food-related motivational effects in food-deprived, but not in non-food-sated, animals suggests that the neural substrates of motivational events do not dissociate along the line between different rewarding stimuli but along the lines between deprivation and nondeprivation.
...