Neurobehavioral effects of prenatal alcohol: Part II. Partial least squares analysis.

@article{Sampson1989NeurobehavioralEO,
  title={Neurobehavioral effects of prenatal alcohol: Part II. Partial least squares analysis.},
  author={Paul D. Sampson and Ann Streissguth and Helen M. Barr and Fred L. Bookstein},
  journal={Neurotoxicology and teratology},
  year={1989},
  volume={11 5},
  pages={
          477-91
        }
}
This paper, the second in a series of three, introduces Partial Least Squares (PLS) methods for assessing the effects of moderate levels of prenatal alcohol exposure on performance and behavior in young school-age children. Studies of human behavioral teratology pose statistical problems for which standard multiple regression methods are inadequate. Prenatal alcohol exposure, the teratogenic "dose," can be assessed only indirectly through a variety of measures of alcohol consumption. Similarly… Expand
Neurobehavioral effects of prenatal alcohol: Part III. PLS analyses of neuropsychologic tests.
TLDR
The use of Partial Least Squares for data reduction and analysis of 158 neurobehavioral measures as they relate to 13 aspects of prenatal alcohol Exposure suggests a possible "nonverbal learning disability" pattern of deficit associated with prenatal alcohol exposure at the level of social drinking. Expand
The Effects of prenatal alcohol exposure on adolescent cognitive processing: A speed-accuracy tradeoff
Abstract A large literature of experimental animal research, clinical studies of Fetal Alcohol Syndrome (FAS), and prospective longitudinal human studies has established the causal role of alcohol inExpand
Neurobehavioral effects of prenatal alcohol: Part I. Research strategy.
TLDR
A large group of tests assembled to assess neurobehavioral outcomes of alcohol teratogenesis in 7-year-old children are described and their relationships with an alcohol binge score and with full-scale IQ are discussed. Expand
Prenatal exposure to alcohol and school problems in late childhood: A longitudinal prospective study
The population-based Seattle Longitudinal Prospective Study on Alcohol and Pregnancy unites the fields of developmental psychopathology and behavioral teratology. Examining prenatal biologicalExpand
Prenatal alcohol exposure and academic achievement at age six: a nonlinear fit.
TLDR
The relationship was partially reduced by the addition of IQ to the model, but prenatal alcohol exposure still predicted significant deficits in achievement, even after controlling for IQ. Expand
Moderate prenatal alcohol exposure: effects on child IQ and learning problems at age 7 1/2 years.
TLDR
This study shows that alcohol use patterns within the social drinking range can have long lasting effects on IQ and learning problems in young school aged children. Expand
The impact of maternal age on the effects of prenatal alcohol exposure on attention.
TLDR
Findings are consistent with previous findings that children born to older alcohol-using women have more deleterious effects of prenatal alcohol exposure on other neurobehavioral outcomes. Expand
IQ at Age 4 in Relation to Maternal Alcohol Use and Smoking During Pregnancy
Examined the relationship of prenatal alcohol exposure to the IQ of children at age 4 in a longitudinal prospective, population-based study. Multiple-regression analyses on data from 421 childrenExpand
Maternal drinking during pregnancy: attention and short-term memory in 14-year-old offspring--a longitudinal prospective study.
TLDR
The 14-year attention/memory deficits observed in the present study appear to be the adolescent sequelae of deficits observed earlier in development, as is usual in such studies, not all exposed offspring showed deficits. Expand
Prenatal alcohol and marijuana exposure: effects on neuropsychological outcomes at 10 years.
TLDR
Prenatal alcohol use was found to have a significant negative impact on learning and memory skills, as measured by the WRAML, and the effects of prenatal marijuana exposure persisted when other predictors oflearning and memory were controlled. Expand
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Neurobehavioral effects of prenatal alcohol: Part III. PLS analyses of neuropsychologic tests.
TLDR
The use of Partial Least Squares for data reduction and analysis of 158 neurobehavioral measures as they relate to 13 aspects of prenatal alcohol Exposure suggests a possible "nonverbal learning disability" pattern of deficit associated with prenatal alcohol exposure at the level of social drinking. Expand
Neurobehavioral effects of prenatal alcohol: Part I. Research strategy.
TLDR
A large group of tests assembled to assess neurobehavioral outcomes of alcohol teratogenesis in 7-year-old children are described and their relationships with an alcohol binge score and with full-scale IQ are discussed. Expand
Studying Alcohol Teratogenesis from the Perspective of the Fetal Alcohol Syndrome: Methodological and Statistical Issues a
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Large data bases and indirect measurement problems suggest factor analytic extensions of current regression methodology, which are proposed in this paper. Expand
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TLDR
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