Neurobehavioral and transcriptional effects of acrylamide in juvenile rats

  title={Neurobehavioral and transcriptional effects of acrylamide in juvenile rats},
  author={Suzanne M. Seale and Qin Fu Feng and Ameeta Kishore Agarwal and Abir T. El-Alfy},
  journal={Pharmacology Biochemistry and Behavior},
Acrylamide is a type-2 alkene monomer with established human neurotoxic effects. While the primary source of human exposure to acrylamide is occupational, other exposure sources include food, drinking water, and smoking. In this study, neurobehavioral assays coupled with transcriptional profiling analysis were conducted to assess both behavioral and gene expression effects induced by acrylamide neurotoxicity in juvenile rats. Acrylamide administration in rat pups induced significant… CONTINUE READING
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