Neuroanatomy of memory.

  title={Neuroanatomy of memory.},
  author={Stuart M. Zola-Morgan and Larry R. Squire},
  journal={Annual review of neuroscience},
Three important developments have occurred in the area of memory during the past decade. The first was the recognition that there is more than one kind of memory (Cohen 1984; Schacter 1987; Squire 1982; Tulving 1985). Declarative memory (or, explicit memory) affords the capacity for con­ scious recollections about facts and events. This is the kind of memory that is usually referred to when the terms "memory" or "remembering" are used in ordinary language. Declarative memory can be contrasted… 

The neural basis of implicit learning and memory: A review of neuropsychological and neuroimaging research

  • P. Reber
  • Psychology, Biology
  • 2013

Septal Modulation of the Working Memory for Voluntary Behavior

In people, the semantic and episodic components of declarative memory might be modulated by different portions of the hippocampal system, with the hippocampus proper playing a stronger role in the regulation of episodic memory, whereas the perirhinal and parahippocampal cortex more strongly mediate semantic memory.

Studies of Human Learning and Memory

Memory and amnesia

  • A. Mayes
  • Psychology, Biology
    Behavioural Brain Research
  • 1995

Entorhinal-hippocampal connections and object memory in the rat: acquisition versus retention

The findings indicate that the role of entorhinal-hippocampal connections may be limited to maintaining some types of information for retention, and suggests that behavioral paradigms that include a measure of retention may be particularly important for characterizing the mnemonic functions of the hippocampal/parahipp hippocampal region.

Memory, amnesia, and the issue of recovered memory: neurobiological aspects.

  • S. Zola
  • Psychology, Biology
    Clinical psychology review
  • 1998

The hippocampus and long-term object memory in the rat

  • N. VnekL. Rothblat
  • Biology, Psychology
    The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1996
Results suggest that the hippocampus and anatomically related structures are particularly important for retaining visual discriminations over long delay intervals, and may clarify the role of the hippocampus in nonspatial memory.

Entorhinal Cortex Lesions Disrupt the Relational Organization of Memory in Monkeys

The findings support the conclusion that the primate hippocampal system critically enables the relational organization of declarative memory.

Immediate Early Genes and the Mapping of Environmental Representations in Hippocampal Neural Networks

The hippocampus has received much attention by researchers interested in understanding the nature of “declarative” or “explicit” memory—the memory for discrete events, which requires conscious



Equivalent impairment of spatial and nonspatial memory following damage to the human hippocampus

This study compared spatial and nonspatial memory in amnesic patients with lesions of the hippocampal formation or diencephalon and suggested that the hippocampus is not especially involved in spatial memory, while cognitive mapping in its most abstract sense may describe hippocampal function.

Declarative and Nondeclarative Memory: Multiple Brain Systems Supporting Learning and Memory

  • L. Squire
  • Psychology, Biology
    Journal of Cognitive Neuroscience
  • 1992
A brain-systems framework for understanding memory phenomena is developed in light of lesion studies involving rats, monkeys, and humans, as well as recent studies with normal humans using the divided visual field technique, event-related potentials, and positron emission tomography (PET).

Implicit memory: History and current status.

Memory for a recent event can be expressed explicitly, as conscious recollection, or implicitly, as a facilitation of test performance without conscious recollection. A growing number of recent

How many memory systems are there

Memory is made up of a number of interrelated systems, organized structures of operating components consisting of neural substrates and their behavioral and cognitive correlates. A ternary clas-

Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans.

  • L. Squire
  • Biology, Psychology
    Psychological review
  • 1992
The role of the hippocampus is considered, which is needed temporarily to bind together distributed sites in neocortex that together represent a whole memory.

The medial temporal lobe memory system

The medial temporal lobe memory system is needed to bind together the distributed storage sites in neocortex that represent a whole memory, but the role of this system is only temporary, as time passes after learning, memory stored in neoc cortex gradually becomes independent of medialporal lobe structures.

The neuropathology of amnesia

The hippocampus, memory, and space

This publication was the first of a new era of work on the neuroanatomy of memory, and signalled the successful establishment of an animal model of human amnesia in the non-human primate.

The primate hippocampal formation: evidence for a time-limited role in memory storage.

Results show that the hippocampal formation is required for memory storage for only a limited period of time after learning, and as time passes, its role in memory diminishes, and a more permanent memory gradually develops independently of the hippocampus.