Neuroanatomical and neurochemical bases of theory of mind

@article{AbuAkel2011NeuroanatomicalAN,
  title={Neuroanatomical and neurochemical bases of theory of mind},
  author={Ahmad M. Abu-Akel and Simone G. Shamay-Tsoory},
  journal={Neuropsychologia},
  year={2011},
  volume={49},
  pages={2971-2984}
}
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458 Citations
Highly Influential Citations
25
Background Citations
175
Methods Citations
19
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458 Citations

Towards a neurocognitive theory of mind: how control and reasoning processes contribute to adult mentalizing
TLDR
A neurocognitive account of ToM should describe a flexible system which adapts to the specific conceptual and contextual demands of the social world at that time, as well as identifying two accounts of control processes for ToM in vlPFC and dmPFC.
Neurofunctional Correlates of Theory of Mind Deficits in Schizophrenia
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The issue of neurofunctional correlates of Theory of Mind deficits in schizophrenia is addressed by reviewing functional imaging studies of the past ten years comparing schizophrenia patients to healthy controls, and several differences in hemodynamic response between patients and controls were observed.
Theory of Mind Skills Are Related to Resting-State Frontolimbic Connectivity in Schizophrenia
TLDR
Differences in the pattern of the resting-state frontolimbic connectivity and its associations with performance in ToM tasks between the two study groups might represent a different setup for processing social information in patients with SCH.
Cognitive and affective Theory of Mind in neurodegenerative diseases: Neuropsychological, neuroanatomical and neurochemical levels
Theory of Mind and Empathy as Multidimensional Constructs: Neurological Foundations
TLDR
It is proposed that a balanced activation of these 2 networks is required for appropriate social behavior: an emotional system and a cognitive system.
Shared Neural Circuits for Mentalizing about the Self and Others
TLDR
It is demonstrated that identical neural circuits are implementing processes involved in mentalizing of both self and other and that the nature of such processes may be the integration of low-level embodied processes within higher level inference-based mentalizing.
Evidence of the role of the cerebellum in cognitive theory of mind using voxel-based lesion mapping
TLDR
This study is the first to reveal direct causal neuropsychological evidence for a role of the cerebellum in some but not all types of ToM, processing, and reinforces the idea that social cognition relies on a complex network functionally connected through white matter pathways that include the Cerebellum.
Distinct neural substrates of affective and cognitive theory of mind impairment in semantic dementia
TLDR
Overall, this study addressed for the first time the neuroanatomical substrates of both cognitive and affective ToM disruption in semantic dementia, highlighting disturbed connectivity within the networks that sustain these abilities.
The overlapping relationship between emotion perception and theory of mind
Common and distinct neural mechanisms of the fundamental dimensions of social cognition
TLDR
The results showed that several brain areas associated with mentalizing, along with the inferior parietal gyrus in the mirror system, showed overlap in response to both agentic and communal words, suggesting that both content categories are related to the neural basis of social cognition.
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References

SHOWING 1-10 OF 193 REFERENCES
Dissociable prefrontal networks for cognitive and affective theory of mind: A lesion study
The ventromedial prefrontal cortex is involved in understanding affective but not cognitive theory of mind stories
TLDR
In the VM group, performance in the affective ToM was significantly impaired as compared to cognitive ToM stories, and ratings of levels of emotionality of each story suggested that levels of affective load correlated with number of errors in the stories, indicating that the more the emotional load involved in the story the greater the difficulty posed for the subjects in this group.
A neurobiological mapping of theory of mind
  • A. Abu-Akel
  • Psychology, Biology
    Brain Research Reviews
  • 2003
Neuroanatomical Evidence for Distinct Cognitive and Affective Components of Self
TLDR
It is found that distinct neural circuits in adjacent regions of the prefrontal cortex subserve cognitive and emotional aspects of self-reflection, and the medial prefrontal cortex responded only to material that was self-descriptive, and this did not differ as a function of the valence of the trait.
Functional connectivity of human striatum: a resting state FMRI study.
TLDR
This work provides a comprehensive functional connectivity analysis of basal ganglia circuitry in humans through a functional magnetic resonance imaging examination during rest and revealed subtler distinctions within striatal subregions not previously appreciated by task-based imaging approaches.
Functional heterogeneity in cingulate cortex: the anterior executive and posterior evaluative regions.
TLDR
There is a fundamental dichotomy between the functions of anterior and posterior cingulate cortices, which subserves primarily executive functions related to the emotional control of visceral, skeletal, and endocrine outflow and evaluation of spatial orientation and memory.
Social brain dysfunctions in schizophrenia: A review of neuroimaging studies
Understanding orbitofrontal contributions to theory-of-mind reasoning: Implications for autism
  • M. Sabbagh
  • Psychology, Biology
    Brain and Cognition
  • 2004
Shared Neural Circuits for Mentalizing about the Self and Others
TLDR
It is demonstrated that identical neural circuits are implementing processes involved in mentalizing of both self and other and that the nature of such processes may be the integration of low-level embodied processes within higher level inference-based mentalizing.
Dissociating cognitive from affective theory of mind: A TMS study
...
...