Neuroanatomical Diversity of Corpus Callosum and Brain Volume in Autism: Meta-analysis, Analysis of the Autism Brain Imaging Data Exchange Project, and Simulation

@article{Lefebvre2015NeuroanatomicalDO,
  title={Neuroanatomical Diversity of Corpus Callosum and Brain Volume in Autism: Meta-analysis, Analysis of the Autism Brain Imaging Data Exchange Project, and Simulation},
  author={Aline Lefebvre and Anita Beggiato and Thomas Bourgeron and Roberto Toro},
  journal={Biological Psychiatry},
  year={2015},
  volume={78},
  pages={126-134}
}
  • Aline Lefebvre, Anita Beggiato, +1 author Roberto Toro
  • Published 2015
  • Psychology, Medicine
  • Biological Psychiatry
  • BACKGROUND Patients with autism have been often reported to have a smaller corpus callosum (CC) than control subjects. METHODS We conducted a meta-analysis of the literature, analyzed the CC in 694 subjects of the Autism Brain Imaging Data Exchange project, and performed computer simulations to study the effect of different analysis strategies. RESULTS Our meta-analysis suggested a group difference in CC size; however, the studies were heavily underpowered (20% power to detect Cohen's d… CONTINUE READING

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    A Meta-Analysis of the Corpus Callosum in Autism

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