Neuroactive steroids and affective disorders.

  title={Neuroactive steroids and affective disorders.},
  author={Daniela Eser and Cornelius Schuele and Thomas C. Baghai and Elena Romeo and Doncho P. Uzunov and Rainer Rupprecht},
  journal={Pharmacology, biochemistry, and behavior},
  volume={84 4},
Neuroactive steroids modulate neurotransmission through modulation of specific neurotransmitter receptors such as gamma-aminobutyric acid type A (GABA(A)) receptors. Preclinical studies suggested that neuroactive steroids may modulate anxiety and depression-related behaviour and may contribute to the therapeutical effects of antidepressant drugs… CONTINUE READING