Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post-finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology.

@article{Melcangi2013NeuroactiveSL,
  title={Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post-finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology.},
  author={R. Melcangi and D. Caruso and F. Abbiati and S. Giatti and D. Calabrese and F. Piazza and G. Cavaletti},
  journal={The journal of sexual medicine},
  year={2013},
  volume={10 10},
  pages={
          2598-603
        }
}
  • R. Melcangi, D. Caruso, +4 authors G. Cavaletti
  • Published 2013
  • Psychology, Medicine
  • The journal of sexual medicine
  • INTRODUCTION Observations performed in a subset of subjects treated with finasteride (an inhibitor of the enzyme 5α-reductase) for male pattern hair loss seem to indicate that sexual dysfunction as well as anxious/depressive symptomatology may occur at the end of the treatment and continue after discontinuation. AIM A possible hypothesis to explain depression symptoms after finasteride treatment might be impairment in the levels of neuroactive steroids. Therefore, neuroactive steroid levels… CONTINUE READING
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