Neuro-glial cannabinoid receptors modulate signaling in the embryonic avian retina

@article{Kubrusly2018NeuroglialCR,
  title={Neuro-glial cannabinoid receptors modulate signaling in the embryonic avian retina},
  author={Regina C{\'e}lia Cussa Kubrusly and Alexander G{\"u}nter and Luzia da Silva Sampaio and Roberta Silva Martins and Clarissa S. Schitine and Priscila Martins Pinheiro Trindade and Arlete Fernandes and Rosa T. Borelli‐T{\^o}rres and Vivian Sayuri Miya-Coreixas and Anna Carolina Rego Costa and H{\'e}rcules Rezende Freitas and Patrı́cia Franca Gardino and Fernando Garcia de Mello and Karin Costa Calaza and Ricardo A. M. Reis},
  journal={Neurochemistry International},
  year={2018},
  volume={112},
  pages={27-37}
}
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References

SHOWING 1-10 OF 93 REFERENCES
Roles of cannabinoid receptors type 1 and 2 on the retinal function of adult mice.
TLDR
The data indicated that CB2R is likely to be involved in shaping retinal responses to light and suggest that CB1 and CB2 receptors could have different roles in visual processing.
Cannabinoid CB1 receptor signaling dichotomously modulates inhibitory and excitatory synaptic transmission in rat inner retina
TLDR
This unique feature of CB1R-mediated retrograde regulation provides a novel mechanism for modulating excitatory synaptic transmission in the inner retina, suggesting that endocannabinoid is indeed released from RGCs.
Expression of CB2 cannabinoid receptor mRNA in adult rat retina
TLDR
The presence of CB2 in retina provides new evidence for the presence ofCB2 in the central nervous system (CNS) and an excellent model for its study.
Cannabinoid CB1 receptors and ligands in vertebrate retina: localization and function of an endogenous signaling system.
TLDR
The presence and distribution of the CB1 receptor, the large amounts of 2-arachidonylglycerol found, and the effects of cannabinoids on calcium channel activity in bipolar cells suggest a substantive role for an endogenous cannabinoid signaling system in retinal physiology, and perhaps vision in general.
Glutathione-Induced Calcium Shifts in Chick Retinal Glial Cells
TLDR
The data suggest that GSH, in addition to antioxidant effects, could act signaling calcium shifts at the millimolar range particularly in Müller glia, and could regulate the release of GABA, with additional protective effects on retinal neuron-glial circuit.
Functional plasticity of GAT-3 in avian Müller cells is regulated by neurons via a glutamatergic input
Functional expression of cell surface cannabinoid CB1 receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons
Expression of functional receptors and transmitter enzymes in cultured Muller cells
Ethanol increases GABA release in the embryonic avian retina
Cannabinoid Receptor CB2 Modulates Axon Guidance
TLDR
In vitro and in vivo evidences are presented that the cannabinoid receptor 2 (CB2R) is expressed along the retino-thalamic pathway and exerts a modulatory action on axon guidance and demonstrates that the contribution of endocannabinoids to brain development is not solely mediated by CB1R, but also involves CB2R.
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