Neurexin-1 regulates sleep and synaptic plasticity in Drosophila melanogaster.


Neurexins are cell adhesion molecules that are important for synaptic plasticity and homeostasis, although links to sleep have not yet been investigated. We examined the effects of neurexin-1 perturbation on sleep in Drosophila, showing that neurexin-1 nulls displayed fragmented sleep and altered circadian rhythm. Conversely, the over-expression of neurexin… (More)
DOI: 10.1111/ejn.13023


Cite this paper

@article{Larkin2015Neurexin1RS, title={Neurexin-1 regulates sleep and synaptic plasticity in Drosophila melanogaster.}, author={Aoife E Larkin and Ming-Yu Chen and Leonie Kirszenblat and Judith R Reinhard and Bruno van Swinderen and Charles Claudianos}, journal={The European journal of neuroscience}, year={2015}, volume={42 7}, pages={2455-66} }