Neuregulin-regulated gene expression in mammary carcinoma cells.


Recent studies have suggested that autocrine production of Neuregulin (NRG), a growth factor that activates members of the Epidermal Growth Factor Receptor/ErbB family of proto-oncogenes, is sufficient for breast tumor initiation and progression. To elucidate the molecular mechanisms regulating these events, we undertook a global analysis of genes regulated… (More)

5 Figures and Tables


  • Presentations referencing similar topics