Neuregulin induces GABA(A) receptor subunit expression and neurite outgrowth in cerebellar granule cells.

@article{Rieff1999NeuregulinIG,
  title={Neuregulin induces GABA(A) receptor subunit expression and neurite outgrowth in cerebellar granule cells.},
  author={Heather I. Rieff and Lori Therese Raetzman and Douglas W. Sapp and Hermes H. Yeh and Ruth E. Siegel and Gabriel Corfas},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1999},
  volume={19 24},
  pages={10757-66}
}
Neuregulin (NRG), a growth and differentiation factor that signals via erbB receptor tyrosine kinases, has been shown to have biological effects in both the CNS and the peripheral nervous system. We report here that erbB4 is expressed in mature cerebellar granule cells, where it appears to be concentrated at the granule cell postsynaptic terminals. We also… CONTINUE READING