Neural systems supporting interoceptive awareness

  title={Neural systems supporting interoceptive awareness},
  author={Hugo D. Critchley and Stefan Wiens and Pia Rotshtein and Arne {\"O}hman and Raymond J. Dolan},
  journal={Nature Neuroscience},
Influential theories of human emotion argue that subjective feeling states involve representation of bodily responses elicited by emotional events. Within this framework, individual differences in intensity of emotional experience reflect variation in sensitivity to internal bodily responses. We measured regional brain activity by functional magnetic resonance imaging (fMRI) during an interoceptive task wherein subjects judged the timing of their own heartbeats. We observed enhanced activity in… 

How does interoceptive awareness interact with the subjective experience of emotion? An fMRI Study

Recent studies in cognitive neuroscience have suggested that the integration of information about the internal bodily state and the external environment is crucial for the experience of emotion.

Neural systems connecting interoceptive awareness and feelings

It is concluded that the perception of bodily states is a crucial determinant for the processing and the subjective experience of feelings.

Psychophysiology of neural, cognitive and affective integration: fMRI and autonomic indicants

  • H. Critchley
  • Psychology, Biology
    International journal of psychophysiology : official journal of the International Organization of Psychophysiology
  • 2009

Anterior insular cortex mediates bodily sensibility and social anxiety.

The results indicated that right anterior insular activation was positively correlated with individual levels of social anxiety and neuroticism and negatively correlated with agreeableness and extraversion, and suggest that attention to interoceptive sensation affects personality traits through how the authors feel emotion subjectively in various situations.

The Embodiment of Emotional Feelings in the Brain

It is shown that experience of core and body–boundary–violation disgust are dissociable in both peripheral autonomic and central neural responses and also that emotional experience specific to anterior insular activity encodes these different underlying patterns of peripheral physiological responses.

Affective interoceptive inference: Evidence from heart‐beat evoked brain potentials

It is found that affective predictions of external socially relevant information modulated the heartbeat‐evoked potential, a marker of cardiac interoception, and the affective repetition effects were dependent on repetition probability, highlighting the influence of top‐down exteroceptive predictions onInteroception.

Interoception and emotion: Shared mechanisms and clinical implications

This chapter will approach the relationship between interoception and emotion within the interoceptive predictive processing framework and describe how emotional states could be the product ofInteroceptive prediction error minimization.

Modulation of Emotional Appraisal by False Physiological Feedback during fMRI

The findings identify the neural substrates supporting behavioural effects of false physiological feedback, and highlight mechanisms that underlie subjective anxiety states, including the importance of the right anterior insula in guiding second-order “cognitive” representations of bodily arousal state.



Neuroanatomical basis for first- and second-order representations of bodily states

These findings provide empirical support for a theory proposing a hierarchical representation of bodily states and an absence of afferent feedback concerning autonomically generated bodily states was associated with subtle impairments of emotional responses in PAF patients.

Regional Brain Activation Due to Pharmacologically Induced Adrenergic Interoceptive Stimulation in Humans

These results demonstrate the involvement of specific brain regions as well as hemispheric laterality of function in visceral perception, and suggest that during emotional reactions involving changes in visceral organ function, activation of some of the brain regions observed could be due specifically to interoceptive processes.

Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence.

Converging neuroimaging and clinical findings suggest that ACC function mediates context-driven modulation of bodily arousal states during effortful cognitive and motor behaviour.

Thermosensory activation of insular cortex

Using positron emission tomography, it is found contralateral activity correlated with graded cooling stimuli only in the dorsal margin of the middle/posterior insula in humans, which supports the proposal that central pain results from loss of the normal inhibition of pain by cold.

Visceral perception, anhedonia, and emotion

Cerebral correlates of autonomic cardiovascular arousal: a functional neuroimaging investigation in humans

Evidence is provided for the involvement of areas previously implicated in cognitive and emotional behaviours in the representation of peripheral autonomic states, consistent with a functional organization that produces integrated cardiovascular response patterns in the service of volitional andotional behaviours.

Heartbeat detection and the experience of emotions

Although many theories of emotion hypothesise a crucial role for the self-perception of visceral activity, there has been little empirical investigation of the relationship between visceral

Functional Neuroimaging of Visceral Sensation

  • Q. AzizA. SchnitzlerP. Enck
  • Biology, Psychology
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
  • 2000
It is likely that future research into the factors that modulate the brain processing of visceral sensation in health and disease are likely to improve further the understanding of the pathophysiology of functional visceral pain disorders.