Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice


Existing protocols for the neural differentiation of mouse embryonic stem (ES) cells require extended in vitro culture, yield variable differentiation results or are limited to the generation of selected neural subtypes. Here we provide a set of coculture conditions that allows rapid and efficient derivation of most central nervous system phenotypes. The… (More)
DOI: 10.1038/nbt870


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