Neural stem cells and cholinergic neurons: regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor.

@article{Calz2003NeuralSC,
  title={Neural stem cells and cholinergic neurons: regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor.},
  author={Laura Calz{\`a} and Alessandro Giuliani and Mercedes Fern{\'a}ndez and Stefania Pirondi and Giulia D'Intino and Luigi Aloe and Luciana Giardino},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2003},
  volume={100 12},
  pages={7325-30}
}
Degenerative diseases represent a severe problem because of the very limited repair capability of the nervous system. To test the potential of using stem cells in the adult central nervous system as "brain-marrow" for repair purposes, several issues need to be clarified. We are exploring the possibility of influencing, in vivo, proliferation, migration, and phenotype lineage of stem cells in the brain of adult animals with selective neural lesions by exogenous administration (alone or in… CONTINUE READING
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