Neural stem cells: progression of basic research and perspective for clinical application.

@article{Okano2002NeuralSC,
  title={Neural stem cells: progression of basic research and perspective for clinical application.},
  author={Hideyuki Okano},
  journal={The Keio journal of medicine},
  year={2002},
  volume={51 3},
  pages={115-28}
}
It has long been thought that functional regeneration of the injured central nervous system (CNS) is impossible, as Santiago Ramóny Cajal described in the early 20th century, "once the development was ended, the fonts of growth and regeneration ... dried up irrevocably". In mammalian neural development, most neuronal production (neurogenesis) occurs in the embryonic stage. However, recent findings indicate that neurogenesis continues in the olfactory bulb, hippocampus, and dentate gyrus of… CONTINUE READING
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