Neural stem cell-mediated therapy for rare brain diseases: perspectives in the near future for LSDs and MNDs.

@article{Filippis2011NeuralSC,
  title={Neural stem cell-mediated therapy for rare brain diseases: perspectives in the near future for LSDs and MNDs.},
  author={Lidia de Filippis},
  journal={Histology and histopathology},
  year={2011},
  volume={26 8},
  pages={1093-109}
}
Lysosomal storage diseases (LSDs) are genetically inherited disorders affecting most patients in pediatric age and progressively lead to severe, even lethal, multiorgan dysfunction and brain neurodegeneration. Motor neuron diseases (MNDs) or Amyotrophic Lateral Sclerosis (ALS)-related syndromes are neurodegenerative disorders occurring in the majority of cases sporadically and affect adult middle-aged patients. Despite being divergent in most pathological and physiological hallmarks, both MNDs… CONTINUE READING