Neural stem/progenitor cells initiate the formation of cellular networks that provide neuroprotection by growth factor-modulated antioxidant expression.

@article{Madhavan2008NeuralSC,
  title={Neural stem/progenitor cells initiate the formation of cellular networks that provide neuroprotection by growth factor-modulated antioxidant expression.},
  author={Lalitha Madhavan and V{\'a}clav Ourednik and Jitka Ourednik},
  journal={Stem cells},
  year={2008},
  volume={26 1},
  pages={
          254-65
        }
}
Recent studies indicate that transplanted neural stem/progenitor cells (NSPs) can interact with the environment of the central nervous system and stimulate protection and regeneration of host cells exposed to oxidative stress. Here, a set of animals grafted with NSPs and treated with 3-nitropropionic acid (3-NP) exhibited reduced behavioral symptoms and less severe damage of striatal cytoarchitecture than sham transplanted controls including better survival of neurons. Sites of tissue sparing… CONTINUE READING
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