Neural responses during Valsalva maneuvers in obstructive sleep apnea syndrome.

  title={Neural responses during Valsalva maneuvers in obstructive sleep apnea syndrome.},
  author={Luke A. Henderson and Mary A. Woo and Paul M Macey and Katherine E. Macey and Robert C. Frysinger and Jeffry R. Alger and Frisca L. Yan-Go and Ronald M. Harper},
  journal={Journal of applied physiology},
  volume={94 3},
The repetitive upper airway muscle atonic episodes and cardiovascular sequelae of obstructive sleep apnea (OSA) suggest dysfunction of specific neural sites that integrate afferent airway signals with autonomic and somatic outflow. We determined neural responses to the Valsalva maneuver by using functional magnetic resonance imaging. Images were collected during a baseline and three Valsalva maneuvers in 8 drug-free OSA patients and 15 controls. Multiple cortical, midbrain, pontine, and… CONTINUE READING


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