Neural representation of reward in recovered depressed patients

@article{McCabe2009NeuralRO,
  title={Neural representation of reward in recovered depressed patients},
  author={Ciara McCabe and Philip J. Cowen and Catherine J. Harmer},
  journal={Psychopharmacology},
  year={2009},
  volume={205},
  pages={667 - 677}
}
Anhedonia, a loss of interest and pleasure in normally rewarding stimuli, is a key diagnostic criterion for major depression. It has been suggested that deficits in the processing of reward-relevant stimuli could represent an endophenotype for depression. We hypothesized that people at risk of depression by virtue of a personal history of the illness would show impaired neural responses to a primary rewarding stimulus. Using functional magnetic resonance imaging, we measured the neural response… CONTINUE READING

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