Neural regulation of luteinizing hormone secretion in the rat.

  title={Neural regulation of luteinizing hormone secretion in the rat.},
  author={Satya P. Kalra and Pushpa S. Kalra},
  journal={Endocrine reviews},
  volume={4 4},
I. Introduction Essentially, two modalities of luteinizing hormone (LH) secretion have been identified in the rat. The basal mode is characterized by episodic bursts of pituitary LH discharge whose frequency and amplitude may vary considerably during the day in male (1, 2) and according to different phases of the estrous cycle in female rats (4). This low level of pulsatile LH secretion is established early in the juvenile period (5). With advancing age, subtle and progressive disintegration of… 
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The Preovulatory Surge of Gonadotropin Releasing Hormone
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Opioid control of luteinizing hormone secretion in humans.
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Dose and time relationships of intravenously injected rat recombinant luteinizing hormone and testicular testosterone secretion in the male Rat.
The novel preparation of rat recLH provides a physiologically relevant tool for studying the complex relationship between pulsatile LH release and T secretion in male rats.
Modulating Mechanisms of Neuroendocrine Cell Activity: The LHRH Pulse Generator
Several lines of evidence are compiled supporting the notion that the pulse generating mechanism resides within the LHRH neuronal network, and put this characteristic of L HRH neurons in perspective with gonadal influences both internal and external to the L hrh neuronal network.
Suppression of the luteinizing hormone surge by chlordimeform in ovariectomized, steroid-primed female rats.
The present study focused on the effect of acute CDF administration on the appearance of the induced LH surge, and found that an indirect adrenal effect was not the principal route, but may accompany an action of CDF on the hypothalamic mechanisms regulating the surge and becomes evident after more prolonged exposure.
Diurnal patterns of pulsatile luteinizing hormone secretion in hypothalamic amenorrhea: reproducibility and responses to opiate blockade and an alpha 2-adrenergic agonist.
Data indicate that slow frequency GnRH secretion is a common finding during the day in women with HA and more variable at night, suggesting that the mechanisms involved in reducing pulsatile Gn RH secretion are less effective during sleep.