Neural regeneration and cell replacement: a view from the eye.

@article{Lamba2008NeuralRA,
  title={Neural regeneration and cell replacement: a view from the eye.},
  author={Deepak Ashok Lamba and Mike O Karl and Thomas A. Reh},
  journal={Cell stem cell},
  year={2008},
  volume={2 6},
  pages={538-49}
}
Neuronal degenerations in the retina are leading causes of blindness. Like most other areas of the CNS, the neurons of the mammalian retina are not replaced following degeneration. However, in nonmammalian vertebrates, endogenous repair processes restore neurons very efficiently, even after complete loss of the retina. We describe the phenomenon of retinal regeneration in nonmammalian vertebrates and attempts made in recent years to stimulate similar regenerative processes in the mammalian… CONTINUE READING