Neural progenitor NT2N cell lines from teratocarcinoma for transplantation therapy in stroke.

@article{Hara2008NeuralPN,
  title={Neural progenitor NT2N cell lines from teratocarcinoma for transplantation therapy in stroke.},
  author={Koichi Hara and Takao Yasuhara and Mina Maki and Noriyuki Matsukawa and Tadashi Masuda and Seong Jin Yu and Mohammed AbdEl-Aziz Mohammed Ali and Guolong Yu and Lin Huao Xu and Seung Up Kim and David C. Hess and Cesario V. Borlongan},
  journal={Progress in neurobiology},
  year={2008},
  volume={85 3},
  pages={318-34}
}
This review article discusses recent progress on the use of teratocarcinoma-derived Ntera2/D1 neuron-like cells (NT2N cells, also called hNT cells) as graft source for cell transplantation in stroke. Laboratory evidence has demonstrated the therapeutic potential of NT2N cells in stroke therapy. Phase I and II clinical trials have shown the cells' feasibility, safety and tolerability profiles in stroke patients. Despite these novel features of NT2N cells, the transplantation regimen remains to… CONTINUE READING
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