Neural precursor cells derived from human embryonic brain retain regional specificity.

@article{Horiguchi2004NeuralPC,
  title={Neural precursor cells derived from human embryonic brain retain regional specificity.},
  author={Satoshi Horiguchi and Jun Takahashi and Yo Kishi and Asuka Morizane and Yo Okamoto and Masaomi Koyanagi and Masayuki Tsuji and K. Tashiro and T. Honjo and Shingo Fujii and N. Hashimoto},
  journal={Journal of neuroscience research},
  year={2004},
  volume={75 6},
  pages={817-24}
}
Recent studies have revealed that neural precursor cells can be expanded not only from the subventricular zone and hippocampus but also from other regions of the human embryonic brain. To determine the regional differences of these precursor cells, we divided the brain of a 9-week-old human embryo into four parts, i.e., telencephalon, diencephalon, mesencephalon, and rhombencephalon. All cultures of the tissues yielded neurospheres, and these spheres gave rise to neurons, astrocytes, and… CONTINUE READING