Neural mechanisms of navigation involving interactions of cortical and subcortical structures.

@article{Hinman2018NeuralMO,
  title={Neural mechanisms of navigation involving interactions of cortical and subcortical structures.},
  author={James R. Hinman and Holger Dannenberg and Andrew S. Alexander and Michael E. Hasselmo},
  journal={Journal of neurophysiology},
  year={2018},
  volume={119 6},
  pages={
          2007-2029
        }
}
Animals must perform spatial navigation for a range of different behaviors, including selection of trajectories toward goal locations and foraging for food sources. To serve this function, a number of different brain regions play a role in coding different dimensions of sensory input important for spatial behavior, including the entorhinal cortex, the retrosplenial cortex, the hippocampus, and the medial septum. This article will review data concerning the coding of the spatial aspects of… 

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References

SHOWING 1-10 OF 371 REFERENCES
Head direction cells and the neurophysiological basis for a sense of direction
  • J. Taube
  • Biology, Psychology
    Progress in Neurobiology
  • 1998
Mapping of a non-spatial dimension by the hippocampal/entorhinal circuit
TLDR
Neurons involved in this representation overlapped with the known spatial cell types in the circuit, such as place cells and grid cells, suggesting that common circuit mechanisms in the hippocampal–entorhinal system are used to represent diverse behavioural tasks, possibly supporting cognitive processes beyond spatial navigation.
Place cells, navigational accuracy, and the human hippocampus.
TLDR
The left human hippocampus retains its role in spatial mapping as demonstrated by its activation during accurate navigation in imagined and virtual reality environments and may have taken on wider memory functions, perhaps by the incorporation of a linear time tag.
A Computational Model for Spatial Navigation Based on Reference Frames in the Hippocampus, Retrosplenial Cortex, and Posterior Parietal Cortex
TLDR
A computational model of the posterior parietal cortex and the retrosplenial cortex for spatial navigation is constructed and shows how low confidence in a reference frame can lead to fluid adaptation and deployment of alternative navigation strategies.
Vestibular and attractor network basis of the head direction cell signal in subcortical circuits
TLDR
Some of the recent studies arguing that the origin of the HD signal resides subcortically, specifically within the reciprocal connections of the dorsal tegmental and lateral mammillary nuclei are summarized.
Path integration and the neural basis of the 'cognitive map'
TLDR
Theoretical studies suggest that the medial entorhinal cortex might perform some of the essential underlying computations by means of a unique, periodic synaptic matrix that could be self-organized in early development through a simple, symmetry-breaking operation.
Retrosplenial cortex maps the conjunction of internal and external spaces
TLDR
The retrosplenial cortex has the requisite dynamics to serve as an intermediary between brain regions generating different forms of spatial mapping, a result that is consistent with navigational and episodic memory impairments following damage to this region in humans.
The Human Retrosplenial Cortex and Thalamus Code Head Direction in a Global Reference Frame
TLDR
Consistent with the rodent literature, the human thalamus may integrate visual and body-based, orientation cues; global reference frame cues can be used to integrate HD across separate individual locales; and immersive training procedures providing full body- based cues may help to elucidate the neural mechanisms supporting spatial navigation.
Anchoring the neural compass: Coding of local spatial reference frames in human medial parietal lobe
The neural systems that code for location and facing direction during spatial navigation have been investigated extensively; however, the mechanisms by which these quantities are referenced to
Head Direction, Place, and Movement Correlates for Cells in the Rat Retrosplenial Cortex
TLDR
The fact that the retrosplenial cortex contains spatial and movement-related signals and is connected with the motor cortex suggests that it may play a role in path integration or navigational motor planning.
...
...