Neural mechanisms of autonomic, affective, and cognitive integration

@article{Critchley2005NeuralMO,
  title={Neural mechanisms of autonomic, affective, and cognitive integration},
  author={Hugo D. Critchley},
  journal={Journal of Comparative Neurology},
  year={2005},
  volume={493}
}
  • H. Critchley
  • Published 5 December 2005
  • Psychology, Biology
  • Journal of Comparative Neurology
Influential theoretical models propose a central role for afferent information from the body in the expression of emotional feeling states. Feedback representations of changing states of bodily arousal influence learning and facilitate concurrent and prospective decision‐making. Functional neuroimaging studies have increased understanding of brain mechanisms that generate changes in autonomic arousal during behavior and those which respond to internal feedback signals to influence subjective… 
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References

SHOWING 1-10 OF 116 REFERENCES

Anterior cingulate activity during error and autonomic response

Neural systems supporting interoceptive awareness

In right anterior insular/opercular cortex, neural activity predicted subjects' accuracy in the heartbeat detection task and local gray matter volume correlated with both interoceptive accuracy and subjective ratings of visceral awareness.

The human cortex responds to an interoceptive challenge.

  • H. Critchley
  • Psychology, Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2004
The authors undertook a PET study to examine changes in regional brain activity during states of low blood glucose (hypoglycemia), which evoked sympathetic and parasympathetic autonomic arousal, apparent in a range of physiological and neuroendocrine measures.

The Contribution of the Anterior Cingulate Cortex to Executive Processes in Cognition

Results using event-related fMRI confirm that the anterior cingulate cortex does show error related activity but that the same region of the brain also shows increased response related activity during correct responses associated with response competition, suggesting a re-conceptualization of the contribution of the ACC to executive processes that support an evaluative role.

Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence.

Converging neuroimaging and clinical findings suggest that ACC function mediates context-driven modulation of bodily arousal states during effortful cognitive and motor behaviour.

Prefrontal cortical control of the autonomic nervous system: anatomical and physiological observations.

  • E. Neafsey
  • Biology, Psychology
    Progress in brain research
  • 1990

Neural Activity Relating to Generation and Representation of Galvanic Skin Conductance Responses: A Functional Magnetic Resonance Imaging Study

The results suggest that areas implicated in emotion and attention are differentially involved in generation and representation of peripheral SCR responses, and propose that this functional arrangement enables integration of adaptive bodily responses with ongoing emotional and attentional states of the organism.

Cerebral correlates of autonomic cardiovascular arousal: a functional neuroimaging investigation in humans

Evidence is provided for the involvement of areas previously implicated in cognitive and emotional behaviours in the representation of peripheral autonomic states, consistent with a functional organization that produces integrated cardiovascular response patterns in the service of volitional andotional behaviours.

Free will versus survival: Brain systems that underlie intrinsic constraints on behavior

  • J. Price
  • Biology, Psychology
    The Journal of comparative neurology
  • 2005
The amygdala interacts with the cortical sensory systems in the assessment of fear‐related stimuli and modulates the reflex responses through projections to the hypothalamus and brainstem, and the ventromedial prefrontal cortex plays a central role in the ability to discern the consequences of one's actions and make appropriate behavioral choices.

Regret and its avoidance: a neuroimaging study of choice behavior

It is demonstrated that medial orbitofrontal cortex modulates the gain of adaptive emotions in a manner that may provide a substrate for the influence of high-level emotions on decision making.
...