Neural mechanisms of autonomic, affective, and cognitive integration

@article{Critchley2005NeuralMO,
  title={Neural mechanisms of autonomic, affective, and cognitive integration},
  author={Hugo D. Critchley},
  journal={Journal of Comparative Neurology},
  year={2005},
  volume={493}
}
  • H. Critchley
  • Published 2005
  • Psychology, Medicine
  • Journal of Comparative Neurology
Influential theoretical models propose a central role for afferent information from the body in the expression of emotional feeling states. Feedback representations of changing states of bodily arousal influence learning and facilitate concurrent and prospective decision‐making. Functional neuroimaging studies have increased understanding of brain mechanisms that generate changes in autonomic arousal during behavior and those which respond to internal feedback signals to influence subjective… Expand
Psychophysiology of neural, cognitive and affective integration: fMRI and autonomic indicants
  • H. Critchley
  • Psychology, Medicine
  • International journal of psychophysiology : official journal of the International Organization of Psychophysiology
  • 2009
TLDR
Together these neuroimaging and clinical studies highlight the dynamic relationship between mind and body and help identify neural substrates that may translate thoughts into autonomic arousal and bodily states into feelings that can be shared. Expand
The anterior cingulate cortex and event-based modulation of autonomic states.
  • J. Seamans
  • Medicine
  • International review of neurobiology
  • 2021
TLDR
An alternative view is that the anterior cingulate cortex has a prominent role in regulating autonomic states, and may regulate the autonomic and perhaps emotional reactions to events it is representing. Expand
A role for primate subgenual cingulate cortex in sustaining autonomic arousal
TLDR
It is shown that, in macaque monkeys, this small part of the frontal cortex is necessary for sustaining elevated arousal in anticipation of positive emotional events, which suggests a mechanism for the contribution of this area to affective regulation, including an account for the lack of pleasure and passivity that characterizes mood disorders. Expand
Motor, cognitive, and affective areas of the cerebral cortex influence the adrenal medulla
TLDR
Transneuronal transport of rabies virus is used to identify the areas of the primate cerebral cortex that communicate through multisynaptic connections with a major sympathetic effector, the adrenal medulla, to provide an anatomical basis for psychosomatic illness where mental states can alter organ function. Expand
Modulation of Emotional Appraisal by False Physiological Feedback during fMRI
TLDR
The findings identify the neural substrates supporting behavioural effects of false physiological feedback, and highlight mechanisms that underlie subjective anxiety states, including the importance of the right anterior insula in guiding second-order “cognitive” representations of bodily arousal state. Expand
The neural basis of one's own conscious and unconscious emotional states
TLDR
In the framework proposed, emotion generation proceeds through a series of appraisal mechanisms - some of which appear to require more cognitively sophisticated computational processing than others - that ultimately trigger iterative adjustments to one's bodily state. Expand
The nexus between decision making and emotion regulation: A review of convergent neurocognitive substrates
  • D. Mitchell
  • Medicine, Psychology
  • Behavioural Brain Research
  • 2011
TLDR
The idea is raised that key aspects of decision making and emotion regulation are bound by a common functional objective in which internal representations of conditioned stimuli and reinforcers are modulated to facilitate optimal behaviour or states. Expand
How the amygdala affects emotional memory by altering brain network properties
TLDR
Development of electrophysiological and optogenetic techniques in rodents will likely lead to an updated view of the amygdala as a critical nexus within large-scale networks supporting different aspects of memory processing for emotionally arousing experiences. Expand
The role of anterior insular cortex in social emotions
TLDR
A model is presented suggesting that AI is not only involved in representing current states, but also in predicting emotional states relevant to the self and others, and implies that AI plays a dominant role in decision making in complex and uncertain environments. Expand
Hot cognition and activation of the medial prefrontal cortex: Self-regulating in contexts involving motivational pressures
The medial prefrontal cortex (rnPFC) is involved in performance-monitoring and has been implicated in the generation of several e1ectrocortica1 responses associated with self-regulation. TheExpand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 115 REFERENCES
Neuroanatomical basis for first- and second-order representations of bodily states
TLDR
These findings provide empirical support for a theory proposing a hierarchical representation of bodily states and an absence of afferent feedback concerning autonomically generated bodily states was associated with subtle impairments of emotional responses in PAF patients. Expand
Anterior cingulate activity during error and autonomic response
TLDR
Scanned subjects using functional magnetic resonance imaging while they performed numerical versions of the Stroop task suggested that an interface exists within ACC between cognitive and biobehavioral systems in the service of response adaptation, suggesting that ACC supports a generation of integrated bodily responses. Expand
The human cortex responds to an interoceptive challenge.
  • H. Critchley
  • Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2004
TLDR
The authors undertook a PET study to examine changes in regional brain activity during states of low blood glucose (hypoglycemia), which evoked sympathetic and parasympathetic autonomic arousal, apparent in a range of physiological and neuroendocrine measures. Expand
Neural systems supporting interoceptive awareness
TLDR
In right anterior insular/opercular cortex, neural activity predicted subjects' accuracy in the heartbeat detection task and local gray matter volume correlated with both interoceptive accuracy and subjective ratings of visceral awareness. Expand
The Contribution of the Anterior Cingulate Cortex to Executive Processes in Cognition
TLDR
Results using event-related fMRI confirm that the anterior cingulate cortex does show error related activity but that the same region of the brain also shows increased response related activity during correct responses associated with response competition, suggesting a re-conceptualization of the contribution of the ACC to executive processes that support an evaluative role. Expand
Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence.
TLDR
Converging neuroimaging and clinical findings suggest that ACC function mediates context-driven modulation of bodily arousal states during effortful cognitive and motor behaviour. Expand
Prefrontal cortical control of the autonomic nervous system: anatomical and physiological observations.
  • E. Neafsey
  • Psychology, Medicine
  • Progress in brain research
  • 1990
TLDR
The relationship of the prefrontal cortex to emotion, visceral function and emotion are closely associated, and the visceral regions of prefrontal cortex are likely to be brain areas whose activity contributes to psychosomatic disease are reviewed. Expand
Neural Activity Relating to Generation and Representation of Galvanic Skin Conductance Responses: A Functional Magnetic Resonance Imaging Study
TLDR
The results suggest that areas implicated in emotion and attention are differentially involved in generation and representation of peripheral SCR responses, and propose that this functional arrangement enables integration of adaptive bodily responses with ongoing emotional and attentional states of the organism. Expand
Cerebral correlates of autonomic cardiovascular arousal: a functional neuroimaging investigation in humans
TLDR
Evidence is provided for the involvement of areas previously implicated in cognitive and emotional behaviours in the representation of peripheral autonomic states, consistent with a functional organization that produces integrated cardiovascular response patterns in the service of volitional andotional behaviours. Expand
Free will versus survival: Brain systems that underlie intrinsic constraints on behavior
  • J. Price
  • Biology, Medicine
  • The Journal of comparative neurology
  • 2005
TLDR
The amygdala interacts with the cortical sensory systems in the assessment of fear‐related stimuli and modulates the reflex responses through projections to the hypothalamus and brainstem, and the ventromedial prefrontal cortex plays a central role in the ability to discern the consequences of one's actions and make appropriate behavioral choices. Expand
...
1
2
3
4
5
...