Neural lineage-specific homeoprotein BRN2 is directly involved in TTF1 expression in small-cell lung cancer

@article{Sakaeda2013NeuralLH,
  title={Neural lineage-specific homeoprotein BRN2 is directly involved in TTF1 expression in small-cell lung cancer},
  author={Masashi Sakaeda and Hanako Sato and Jun Ishii and Chie Miyata and Hiroshi Kamma and Yukiko Shishido-Hara and Hiroaki Shimoyamada and Masachika Fujiwara and Tetsuya Endo and Ryota Tanaka and Haruhiko Kondo and Tomoyuki Goya and Ichiro Aoki and Takuya Yazawa},
  journal={Laboratory Investigation},
  year={2013},
  volume={93},
  pages={408-421}
}
Thyroid transcription factor 1 (TTF1) plays crucial roles in thyroid, lung, and developing brain morphogenesis. Because TTF1-expressing neoplasms are generated from organs and tissues that normally express TTF1, such as the thyroid follicular epithelium and peripheral lung airway epithelium, TTF1 is widely used as a cell lineage-specific and diagnostic marker for thyroid carcinomas and for lung adenocarcinomas with terminal respiratory unit (TRU) differentiation. However, among lung… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Similar Papers

Loading similar papers…