Neural innervation of white adipose tissue and the control of lipolysis.

  title={Neural innervation of white adipose tissue and the control of lipolysis.},
  author={Timothy J Bartness and Yang Liu and Yogendra B. Shrestha and Vitaly Ryu},
  journal={Frontiers in neuroendocrinology},
  volume={35 4},
White adipose tissue (WAT) is innervated by the sympathetic nervous system (SNS) and its activation is necessary for lipolysis. WAT parasympathetic innervation is not supported. Fully-executed SNS-norepinephrine (NE)-mediated WAT lipolysis is dependent on β-adrenoceptor stimulation ultimately hinging on hormone sensitive lipase and perilipin A phosphorylation. WAT sympathetic drive is appropriately measured electrophysiologically and neurochemically (NE turnover) in non-human animals and this… CONTINUE READING


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