Neural influence on protein kinase C isoform expression in skeletal muscle.

@article{Hilgenberg1996NeuralIO,
  title={Neural influence on protein kinase C isoform expression in skeletal muscle.},
  author={Lutz Hilgenberg and S Yearwood and Stuart Milstein and Kathryn Miles},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1996},
  volume={16 16},
  pages={4994-5003}
}
Protein kinase C (PKC) is a family of enzymes involved in synapse formation and signal transduction at the neuromuscular junction. Two PKC isoforms, classical PKC alpha and novel PKC theta, have been shown to be enriched in skeletal muscle or localized to the endplate. We examined the role of nerve in regulating the expression of these PKC isoforms in rat skeletal muscle by denervating diaphragm muscle and measuring PKC protein expression at various postoperative times. nPKC theta protein… CONTINUE READING