Neural grafting to experimental neocortical infarcts improves behavioral outcome and reduces thalamic atrophy in rats housed in enriched but not in standard environments.

@article{Mattsson1997NeuralGT,
  title={Neural grafting to experimental neocortical infarcts improves behavioral outcome and reduces thalamic atrophy in rats housed in enriched but not in standard environments.},
  author={Bengt Mattsson and Jens Christian S\orensen and Jens Zimmer and Barbro Birgitta Johansson},
  journal={Stroke},
  year={1997},
  volume={28 6},
  pages={1225-31; discussion 1231-2}
}
BACKGROUND AND PURPOSE The purpose of this study was to evaluate whether grafting of fetal neocortical tissue 1 week after focal brain ischemia improved behavioral outcome and reduced secondary thalamic atrophy. METHODS One week after distal ligation of the right middle cerebral artery in spontaneously hypertensive male rats, blocks of fetal neocortex (embryonic day 17) were homografted to rats housed in standard or enriched environments. Control infarcted nongrafted rats were housed in the… CONTINUE READING

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