Neural foundation of human moral reasoning: an ALE meta-analysis about the role of personal perspective

  title={Neural foundation of human moral reasoning: an ALE meta-analysis about the role of personal perspective},
  author={Maddalena Boccia and Claudia Dacquino and Laura Piccardi and Pierluigi Cordellieri and Cecilia Guariglia and Fabio Ferlazzo and S. Ferracuti and Anna Maria Giannini},
  journal={Brain Imaging and Behavior},
Moral sense is defined as a feeling of the rightness or wrongness of an action that knowingly causes harm to people other than the agent. The large amount of data collected over the past decade allows drawing some definite conclusions about the neurobiological foundations of moral reasoning as well as a systematic investigation of methodological variables during fMRI studies. Here, we verified the existence of converging and consistent evidence in the current literature by means of a meta… 

Common and distinct neural networks involved in fMRI studies investigating morality: an ALE meta-analysis

A series of activation likelihood estimation (ALE) meta-analyses revealed a series of common brain areas associated with all moral tasks, but also revealed unique networks associated with each moral modality, suggesting that different moral tasks recruit specialised brain regions.

Morality and the Brain: The Right Hemisphere and Doing Right

The observed preponderance of right hemisphere lesions in individuals with acquired immorality offers a plausible hypothesis that can be tested in clinical settings, and advances in the neuroscience of morality promise to yield potentially transformative clinical and societal benefits.

Breakdown of utilitarian moral judgement after basolateral amygdala damage.

Most of us would regard killing another person as morally wrong, but when the death of one saves multiple others, it can be morally permitted. According to a prominent computational dual-systems

RUNNING HEAD : CEREBELLUM , EMOTION , MORALITY 1 Cerebellum and Emotion in Morality

Analysis of large-scale neuroimaging data analysis demonstrated that brain regions in the cerebellum, the right Crus I and Crus II in particular, were specifically associated with morality in general.

Neural correlates of conventional and harm/welfare-based moral decision-making

The degree to which social norms are processed by a unitary system or dissociable systems remains debated. Much research on children’s social-cognitive judgments has supported the distinction between

Better together? The neural response to moral dilemmas is moderated by the presence of a close other.

We investigated the modulation of neural and behavioral responses to moral dilemmasby the physical presence of a close friend. We argue that the presence of a close othernot only changes the moral

The moral brain and moral behaviour in patients with Parkinson’s disease: a review of the literature

There are no convincing data supporting the hypothesis that dopaminergic treatment or deep brain stimulation of the STN per se interfere with morality in PD patients, although subgroups of patients may display socially unacceptable behaviour.

Morality recruits neural reward circuitry to shape economic decision making

Evidence that morality modulates both the decision making and the outcome evaluation in economic situations is provided, with evidence that people are willing to invest a larger amount of money into a moral project that may benefit society than they are into an immoral project that they think will harm society.

“Would You Allow Your Wife to Dress in a Miniskirt to the Party”?

Preliminary results showed that batterers do not activate moral areas during IPV dilemmas specifically, but do so during GV dilemma, suggesting that decisions about their female partners do not entail moral conflict.

Expectancy effects of pain and disgust in perceptual and moral decisions

Although expectancy effects have been described before (e.g. placebo effect), no one ever questioned their specificity. After all, it might be that when people anticipate pain, they form a



Parsing the neural correlates of moral cognition: ALE meta-analysis on morality, theory of mind, and empathy

Investigating neural activity associated with different facets of moral thought provides evidence that the neural network underlying moral decisions is probably domain-global and might be dissociable into cognitive and affective sub-systems.

Contextual and Perceptual Brain Processes Underlying Moral Cognition: A Quantitative Meta-Analysis of Moral Reasoning and Moral Emotions

A convergent pattern of reliable brain activity for both task categories in regions of the default network is revealed, consistent with the social and contextual information processes supported by this brain network.

Neural correlates of moral judgments in first- and third-person perspectives: implications for neuroethics and beyond

Results indicate that different neural mechanisms appear to be involved in first or third person perspectives in moral cognition, and suggest two possible ways in which the hippocampus may support the process of moral judgment: by the engagement of episodic memory and its role in understanding the behaviors and emotions of others.

Damage to the prefrontal cortex increases utilitarian moral judgements

It is shown that six patients with focal bilateral damage to the ventromedial prefrontal cortex (VMPC), a brain region necessary for the normal generation of emotions, produce an abnormally ‘utilitarian’ pattern of judgements on moral dilemmas that pit compelling considerations of aggregate welfare against highly emotionally aversive behaviours.

How does morality work in the brain? A functional and structural perspective of moral behavior

The main brain areas that have been associated with morality at both structural and functional levels are reviewed and how it can be studied is speculated about.

Integrative Moral Judgment: Dissociating the Roles of the Amygdala and Ventromedial Prefrontal Cortex

Findings support the hypothesis that the amygdala provides an affective assessment of the action in question, whereas the vmPFC integrates that signal with a utilitarian assessment of expected outcomes to yield “all things considered” moral judgments.

Is Morality Unified? Evidence that Distinct Neural Systems Underlie Moral Judgments of Harm, Dishonesty, and Disgust

It is found that the judgment of moral wrongness was subserved by distinct neural systems for each of the different moral areas and that these differences were much more robust than differences in wrongness judgments within a moral area.