Neural correlates of tasting concentrated quinine and sugar solutions.

@article{Zald2002NeuralCO,
  title={Neural correlates of tasting concentrated quinine and sugar solutions.},
  author={David H. Zald and Mathew C Hagen and Jos{\'e} V. Pardo},
  journal={Journal of neurophysiology},
  year={2002},
  volume={87 2},
  pages={
          1068-75
        }
}
Behavioral, ethological, and electrophysiological evidence suggests that the highly unpleasant, bitter taste of a concentrated quinine hydrochloride (QHCL) should activate the human amygdala. In the present study, healthy subjects tasted 0.02 M QHCL or water while regional cerebral blood flow (rCBF) was assayed with H(2)(15)O PET. Subjects were also studied while tasting a pleasant sucrose solution and resting with eyes closed (ECR). Tasting QHCL significantly increased rCBF within the left… 

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