Neural correlates of formal thought disorder in schizophrenia: preliminary findings from a functional magnetic resonance imaging study.

@article{Kircher2001NeuralCO,
  title={Neural correlates of formal thought disorder in schizophrenia: preliminary findings from a functional magnetic resonance imaging study.},
  author={Tilo Kircher and P. F. Liddle and Mick J Brammer and Steven C. R. Williams and Robin MacGregor Murray and Philip K. McGuire},
  journal={Archives of general psychiatry},
  year={2001},
  volume={58 8},
  pages={769-74}
}
BACKGROUND Formal thought disorder (FTD) is a core symptom of schizophrenia, but its pathophysiology is little understood. We examined the neural correlates of FTD using functional magnetic resonance imaging. METHODS Blood oxygenation level-dependent contrast was measured using functional magnetic resonance imaging while 6 patients with schizophrenia and 6 control subjects spoke about 7 Rorschach inkblots for 3 minutes each. In patients, varying degrees of thought-disordered speech were… CONTINUE READING

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